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It has been stated that 1% annual
risk of infection corresponds to an incidence of 100 sputum smear-positive
cases per 100,000 population. There are two
major underlying assumptions necessary for this to be the
case. First, it is assumed that each case infects on average 10
persons per year. Second, each case is on average infectious
for two years. If this is the case, then 100 incident sputum
smear-positive cases will accomplish 2,000 transmissions in the
population, that is they infect 2% of the population which is the risk of
infection in the community. That this is not
always so, and actually probably very rarely so, is shown in the next two
slides. To
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