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The dosage of isoniazid
recommended by WHO and The Union is 5 mg/kg body weight daily
with an acceptable range from 4 to 6 mg/kg. The thrice-weekly dosage
is 10 mg/kg body weight with an acceptable range from 8 to 12 mg/kg. To
facilitate administration of the drug in the field it has proven most
practical to group patients according to pre-defined weight brackets and
then give a predefined number of tablets according to this weight
bracket. The weight brackets shown above are recommended by The
Union and permit a correct dosage across the entire spectrum of the body
weight of tuberculosis patients.
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